Corticotropin-releasing factor receptor 1 (CRFR1/CRHR1), a Corticotropin-Releasing Factor Receptor, is involved in mediating the stress response and anxiety-related behaviors.
Mutations of the receptor reduce anxiety-related behaviors and may be involved in the pathogenesis of Cushing disease.
Multiple isoforms of CRFR1 are produced by alternative splicing.
Applications:Suitable for use in Immunohistochemistry.
Not suitable for use in Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 13ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:Recognizes human CRHR1. Species Crossreactivity: rat.
Isotype:IgG
Calc Applications Abbrev:IHC
Calc Crossreactivity:Hu Rt
Immunogen:Synthetic peptide corresponding to 17aa from the N-terminus of human C RHR1. Species sequence homology: monkey.