Corticotropin-releasing factor receptor 1 (CRFR1/CRHR1), a Corticotropin-Releasing Factor Receptor, is involved in mediating the stress response and anxiety-related behaviors.
Mutations of the receptor reduce anxiety-related behaviors and may be involved in the pathogenesis of Cushing disease.
Multiple isoforms of CRFR1 are produced by alternative splicing.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 1-2ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human CRFR1/CRHR1. Species Crossreactivity: hamster, monkey, mouse, rat, gorilla, gibbon
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Hm Hu Mk Mo Rt
Immunogen：Synthetic peptide corresponding to 16aa from the N-terminus of human CRFR1/CRHR1. Species sequence homology: bat, bovine and equine.
