CCR9, a chemokine receptor, is expressed in thymocytes and T lymphocytes from the small intestine and colon but not in lymphocytes from tonsils, lung, inflamed liver, normal or inflamed skin, inflamed synovium and synovial fluid, breast milk, and seminal fluid (Kunkel et al., 2000).
CCR9 is not detected in natural killer cells, monocytes, eosinophils, basophils, and neutrophils.
CCR9 binds TECK (thymus-expressed chemokine), a CC chemokine expressed in thymus and small intestine.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 2-4ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:Recognizes human CCR9. Species crossreactivity: bat, gibbon, bovine, gorilla, mouse, porcine, rat and sheep.
Isotype:IgG
Calc Applications Abbrev:IHC
Calc Crossreactivity:Bo Hu Mo Po Rt Sh
Immunogen:Synthetic peptide corresponding to 17aa from the C-terminus of human CCR9. Species sequence homology: monkey, canine and equine.