The C3a Anaphylatoxin Receptor mediates the effects of the inflammatory mediator anaphylatoxin C3a, which is released during complement activation.
This receptor stimulates chemotaxis, granule enzyme release, and superoxide anion production.
It also regulates glial cell activation, may be involved in the pathogenesis of asthma, and may promote cell repair.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 17.3ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:Recognizes human C3a Receptor.
Isotype:IgG
Calc Applications Abbrev:IHC
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to 20aa from 2nd extracellular domain of human C3a Receptor. Species sequence homology: gibbon, gorilla, monkey and orangutan.