BIKE is a NAK serine/threonine protein kinase that mediates osteoblast differentiation.
The protein contains a N-terminal serine/threonine kinase domain, a C-terminal bipartite nuclear localization signal and a glutamine-rich region that may function in protein-protein interactions.
At least two mRNA transcript variants, resulting from alternative splicing at the BIKE locus, have been reported.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human BMP2K/BIKE. Species Crossreactivity: gorilla and gibbon.
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to 15aa from the N-terminus of human BMP2K/BIKE. Species sequence homology: mouse.
