The beta-2 adrenoceptor (ADRB2) is an Adrenergic Receptor expressed in smooth muscle and metabolic tissues.
Activation of this receptor induces a decrease in gastrointestinal motility, bronchodilation, vasodilation in skeletal and cardiac muscle, and glycogenolysis in liver.
The beta-2 adrenoceptor is also a major lipolytic receptor in human fat cells and may be involved in obesity.
Agonists of ADRB2 are most widely used for the treatment of asthma.
Applications:Suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:Recognizes human ADRB2. Species Crossreactivity: chimpanzee and gorilla.
Isotype:IgG
Calc Applications Abbrev:IC IHC WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to 18aa from the C-terminus of human ADRB2. Species sequence homology: monkey.