The alpha 1c- Adrenergic Receptor, also known as alpha 1a-adrenoceptor, is activated by epinephrine and norepinephrine.
This receptor mediates calcium release upon ligand binding.
The alpha 1-c adrenoceptor is one of three subtypes of alpha 1-adrenergic receptor (alpha 1 c/a, alpha 1b, and alpha 1d).
The alpha 1c receptor couples to phospholipase C via a GTP-binding protein insensitive to pertussis toxin.
Three isoforms are generated by alternative splicing.
Applications:Suitable for use in Immunohistochemistry and Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 3ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human ADRA1A. Species crossreactivity: gorilla, gibbon, monkey, mouse, rat, bovine, canine, hamster, equine, porcine, rabbit and sheep.
Isotype：IgG
Calc Applications Abbrev：IC IHC
Calc Crossreactivity：Bo Ca Eq Hm Hu Mk Mo Po Rb Rt Sh
Immunogen：Synthetic peptide corresponding to 16aa from 3rd cytoplasmic domain of human ADRA1A. Species sequence homology: bat and guinea pig.
