5-HT7 Receptor (HTR7 )is a serotonin receptor with several functions, including regulation of the circadian rhythm and mediation of smooth-muscle relaxation in the vasculature and GI tract.
HTR7 has been implicated in depression, autistic, and other neuropsychiatric disorders.
Three protein isoforms have been documented: isoform a: 445aa; isoform b: 432aa; isoform d: 479aa.
Applications:Suitable for use in Immunohistochemistry and Immunofluorescence.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Formalin fixed paraffin embedded): 13ug/mlImmunofluorescence: 13ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:Recognizes human 5-HT7.
Isotype:IgG
Calc Applications Abbrev:IF IHC
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to 16aa from the C-terminus of human 5-HT7. Species sequence homology: gorilla.