SLIT-3 (also known as multiple epidermal growth factor-like domain 5 and Slit homolog 3 protein) is a Slit protein.
The 'slit' gene has been shown to play a critical role in central nervous system midline formation.
In addition to SLIT3 there are two additional human 'slit' homologs, which are termed SLIT1 and SLIT2.
Each SLIT gene encodes a putative secreted protein, which contains conserved protein-protein interaction domains including leucine-rich repeats and epidermal growth factor-like motifs, similar to those of the Drosophila protein.
SLIT proteins may also participate in the formation and maintenance of the nervous and endocrine systems by protein-protein interactions.
Slit-3 is a secreted protein predominantly expressed in thyroid.
Multiple isoforms have been reported for this product.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2, 0.01% sodium azide.
Specificity：Recognizes human SLIT-3. Species Crossreactivity: rat, canine, bovine and mouse.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Bo Ca Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa1164-1177 from human SLIT-3.
