SFRP1 also known as FRP, FRP1, SARP2, secreted apoptosis-related protein 2, secreted frizzled-related protein and secreted frizzled-related protein 1 is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of frizzled proteins.
SFRPs act as soluble modulators of Wnt signaling.
SFRP1 and SFRP5 may be involved in determining the polarity of photoreceptor cells in the retina.
SFRP1 is expressed in several human tissues, with the highest levels in heart.
Applications:Suitable for use in Immunofluorescence, ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilutions:Immunofluorescence: 5ug/mlELISA: 1:5000-1:25,000Western Blot: 1:200-1:2000Immunohistochemistry: 1:800Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography
Form：Supplied as a liquid in PBS,, pH 7.2, 0.01% sodium azide.
Specificity：Recognizes human Sfrp1. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E IF IHC WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to a 12aa region of human Sfrp1.
