84-2134-58　LIM (LIM domain kinase 1, LIMK1) 100ug　168332

特徴

• LIM Kinase is also known as LIM-domain containing protein kinase, LIMK-1 and LIMK.
• There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain.
• LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers.
• Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions.
• LIM kinase 1 and LIM kinase 2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain.
• LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development.
• Applications:Suitable for use in Immunofluorescence, ELISA and Western Blot.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:8000-1:36,000Western Blot: 1:500-1:2000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.