84-2134-43　Interleukin 2 (IL-2, IL2, Interleukin-2, T-cell Growth Factor, TCGF) 100ug　168311

特徴

• IL-2 is a member of a family of cytokines, which also includes IL-4, IL-7, IL-9, IL-15 and IL-21.
• All members of this family signal through a receptor complex that includes the common G chain (?c).
• IL-2 signals through a receptor complex consisting of IL-2 specific IL-2 receptor A (CD25), IL-2 receptor B (CD122) and the common G chain (?c).
• The main function of IL-2 is to promote the development of T regulatory cells.
• IL-2 is produced by several cell types including, B cells, ?d T cells, CD4+ T cells, CD8+ T cells, and eosinophils.
• It has been found to be similar to IL-15 in terms of function.
• Both IL-2 and IL-15 are able to facilitate production of immunoglobulins made by B cells and induce the differentiation and proliferation of natural killer cells.
• The primary differences between IL-2 and IL-15 are found in adaptive immune responses: IL-2 participates in maintenance of T-Regs and reduces self-reactive T cells while IL-15 is necessary for maintaining highly specific T cell responses by supporting survival of CD8 memory T cells.
• Applications:Suitable for use in ELISA and Western Blot.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:20,000Western Blot: 1:500-1:2000Optimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months at -20°C.
• Reconstitute with sterile dH2O or PBS.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.