Interferon-G (IFN-G) is a dimerized soluble cytokine that is the only member of the type II class of interferons.
This interferon was originally called macrophage-activating factor, a term now used to describe a larger family of proteins to which IFN-G belongs.
IFN-G, or type II interferon, is a cytokine that is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control.
Aberrant IFN-G expression is associated with a number of autoinflammatory and autoimmune diseases.
The importance of IFN-G in the immune system stems in part from its ability to inhibit viral replication directly, but, most important, derives from its immunostimulatory and immunomodulatory effects.
IFN-G is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once specific immunity develops.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:20,000Western Blot: 1:500-1:2000Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months at -20°C.
Reconstitute with sterile dH2O or PBS.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：chicken
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a lyophilized powder in 0.02M PBS, pH 7.2, 0.01% sodium azide. Reconstitute with sterile dH2O or PBS.
Specificity：Recognizes chicken IFN-G.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Ch
Immunogen：Recombinant protein corresponding to 145aa from chicken IFN-G expressed in yeast..
