84-2134-31　IL-7 (IL7, IL-7 Interleukin 7, Interleukin-7) (Biotin) 100ug　168297

特徴

• Interleukin 7 (IL7) is a lymphoid cell growth factor that affects pre-B, pro-B, and early T cells.
• IL7 was previously known as pre-B cell growth factor and lymphopoietin 1.
• IL7 supports the growth of early B cells from long-term lymphoid bone marrow cultures.
• It is mitogenic to thymocytes and enhances the response of cells to other stimuli such as polyhydroxyalkanoate (PHA) and concanavalin A (ConA).
• IL7 stimulates the proliferation of CD4+/CD8+ cells.
• The proliferative response of thymocytes to IL7 is not affected by the T cell growth factors such as IL2, IL4 and IL6, suggesting that IL7 is capable of stimulating T cell proliferation through a pathway independent of the known T cell growth factors.
• Mature T cells respond to IL7 and Con A, but not to IL7 alone.
• In myeloid lineage cells, IL7 upregulates the production of pro-inflammatory cytokines and stimulates the tumoricidal activity of monocytes/macrophages.
• IL7 is expressed by adherent stromal cells from various tissues.
• Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilutions:ELISA: 1:20,000-1:100,000Western Blot: 1:2000-1:10,000Immunohistochemistry: 1:1000-1:5000Optimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
• Reconstitute with sterile dH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.