FANCF (also called protein FACF or Fanconi anemia group F protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function.
FANCF has also been implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.
FANCF belongs to the multi-subunit Fanconi anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM.
The complex is not found in FA patients.
FANCF is found within the nucleus.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A/G affinity chromatography.
Form:Supplied as a liquid in 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2, 0.01% sodium azide.
Specificity:Recognizes human FANCF. Species Crossreactivity: chimpanzee.
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to the internal region of human FANCF.