hCas5 (Castor) is the human homolog of a Drosophila gene that regulates neurogenesis.
In human neuro-blastoma tumors where a loss of heterozygosity of CASZ1 is noted, hCas functions to suppress the tumorigenicity of cells.
hCas5 is a developmentally regulated transcription factor found in neural and muscle cells.
hCas5 is a Zn finger transcription factor that is predominantly found in the nucleus.
This antibody is designed to facilitate the functional study of this protein and its role in developmental regulation and expression in human tumor tissues.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:10,000-1:50,000Western Blot: 1:500-1:2000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2.
Specificity：Recognizes human Cas5 A. Species Crossreactivity: mouse, chimpanzee, bovine and rat.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Bo Hu Mo Rt
Immunogen：Synthetic peptide corresponding to human Cas5 at N-terminus.
