84-2132-47 CaM Kinase II (Calcium/calmodulin dependent protein kinase II alpha, CaM kinase II alpha, CaM kinase II alpha chain, CaM kinase II alpha subunit, CaM kinase II, CaM kinase II beta) 100ug 168075
84-2132-47 CaM Kinase II (Calcium/calmodulin dependent protein kinase II alpha, CaM kinase II alpha, CaM kinase II alpha chain, CaM kinase II alpha subunit, CaM kinase II, CaM kinase II beta) 100ug 168075
CaM Kinase II (also known as CAMK2 and calcium/calmodulin-dependent protein kinase type II a-chain) is a prominent kinase in the central nervous system that may function in the long-term potentiation of neurotransmitter release.
CaM Kinase II autophosphorylates itself at 286aa which allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state.
CaM Kinase II is composed of four different chains: a, b, g, and d.
The different isoforms assemble into homo-or heteromultimeric holoenzymes composed of 8 to 12 subunits.
This kinase is expressed in brain tissue.
Alternative splicing occurs for this gene product.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:4000-1:20,000Western Blot: 1:1000-1:3000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A/G affinity chromatography.
Form：Supplied as a liquid in 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2, 0.01% sodium azide.
Specificity：Recognizes human CaM Kinasae II. Species Crossreactivity: mouse, rat, canine and orangutan.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Ca Hu Mo Rt
Immunogen：Synthetic peptide corresponding to aa6-23 from human CaM Kinase II.
