84-2131-07　PRMT7 ([Myelin basic protein]-Arginine N-methyltransferase PRMT7, FLJ10640, Histone-arginine N-methyltransferase PRMT7, KIAA1933, Myelin basic protein-arginine N-methyltransferase, Protein arginine methyltransferase 7, Protein arginine N-methyltransferase 7) 100ug　167487

特徴

• Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity.
• At least three types of PRMT enzymes have been identified in mammalian cells.
• These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas.
• These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins.
• The mammalian PRMT family currently consists of 7 members that share two large domains of homology.
• Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.
• Applications:Suitable for use in ELISA and Western Blot.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:128,000Western Blot: 0.3-1ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.