84-2122-10 [取扱停止]KLK5 (Kallikrein-5, Kallikrein-like Protein 2, KLK-L2, Stratum Corneum Tryptic Enzyme, SCTE, UNQ570/PRO1132) 100ug 150594
特徴
- Kallikreins are a subgroup of serine proteases having diverse physiological functions.
- Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers.
- KLK5 is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19.
- Its expression is up-regulated by estrogens and progestins.
- Kallikrein Related Peptidase 5 is secreted and may be involved in desquamation in the epidermis.
- Alternative splicing results in multiple transcript variants encoding the same protein.
- Applications:Suitable for use in ELISA and Western Blot.
- Other applications not tested.
- Recommended Dilution:ELISA: 1:4000Western Blot: 0.1-0.3ug/mlOptimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:100ug
- Host:goat
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by immunoaffinity chromatography.
- Form:Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
- Specificity:Recognizes human KLK5.
- Isotype:IgG
- Calc Applications Abbrev:E WB
- Calc Crossreactivity:Hu
- Immunogen:Synthetic peptide corresponding to 10aa from near the internal region of KLK5. Species sequence homology: rat, canine and bovine.
- Shelf Life:1year
- EU Commodity Code:30021010
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