84-2117-65　［取扱停止］NOS1 (Nitric Oxide Synthase, Brain, Constitutive NOS, NC-NOS, NOS Type I, Neuronal NOS, N-NOS, nNOS, Peptidyl-cysteine S-nitrosylase NOS1, bNOS) 100ug　150079

特徴

• Human nitric oxide synthases are a family of enzymes responsible for the synthesis of nitric oxide from L-arginine and molecular oxygen.
• There are at least three nitric oxide synthases; NOS I, also known as neuronal NOS or nNOS, NOS II, which is referred to as inducible NOS or iNOS and NOS III, also known as endothelial NOS or eNOS.
• As suggested by their nomenclature, these enzymes have different cellular distribution and are subjected to different regulatory mechanisms.
• NOS III, like NOS I, is a constitutive form of NOS and produces picomolar quantities of nitric oxide (NO) which plays a role in signal transmission and results in physiological effects.
• In the gastrointestinal tract, NO plays a protective role where it has direct microbiocidal properties and acts as a first line of mucosal defence against luminal organisms in the stomach.
• Applications:Suitable for use in Immunofluorescence, ELISA, Western Blot and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:64,000Western Blot: 0.3-1ug/mlOptimal dilutions to be determined by the researcher.
• Positive Control:Human Skeletal Muscle Tissue Lysate
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for at least 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.