84-2117-46 [取扱停止]KLRK1 (NKG2-D Type II Integral Membrane Protein, Killer Cell Lectin-like Receptor Subfamily K Member 1, NK Cell Receptor D, NKG2-D-activating NK Receptor, CD314, D12S2489E, NKG2D, FLJ17759, FLJ75772) 100ug 150060
84-2117-46 [取扱停止]KLRK1 (NKG2-D Type II Integral Membrane Protein, Killer Cell Lectin-like Receptor Subfamily K Member 1, NK Cell Receptor D, NKG2-D-activating NK Receptor, CD314, D12S2489E, NKG2D, FLJ17759, FLJ75772) 100ug 150060
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation.
They can also regulate specific humoral and cell-mediated immunity.
NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function.
D12S2489E is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain.
The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells.
The first non-coding exon at the 5' end of the D12S2489E transcript is included in the 3' end of the KLRC4 transcript.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:32,000Western Blot: 0.1-0.3ug/mlOptimal dilutions to be determined by the researcher.
Positive Control:Human Spleen Tissue Lysate
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Specificity:Recognizes human KLRK1.
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to 12aa from near the internal region of KLRK1. Species sequence homology: mouse and rat.