84-2117-09　［取扱停止］Cofilin 2 (Cofilin-2, Cofilin, Muscle Isoform, CFL2) 100ug　150022

特徴

• CFL2 belongs to the actin-binding proteins ADF family that contains 1 ADF-H domain.
• Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner.
• Defects in CFL2 are the cause of nemaline myopathy type 7 (NEM7).
• Applications:Suitable for use in ELISA and Western Blot.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:128,000Western Blot: 0.01-0.03ug/mlOptimal dilutions to be determined by the researcher.
• Positive Control:Human Skeletal Muscle Tissue Lysate
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for at least 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.