84-2115-35 CD244 (Natural Killer Cell Receptor 2B4, NK Cell Activation-inducing Ligand, NAIL, NK Cell Type I Receptor Protein 2B4, NKR2B4, h2B4, SLAM Family Member 4, SLAMF4, Signaling Lymphocytic Activation Molecule 4, 2B4, h2B4) 100ug 146828
84-2115-35 CD244 (Natural Killer Cell Receptor 2B4, NK Cell Activation-inducing Ligand, NAIL, NK Cell Type I Receptor Protein 2B4, NKR2B4, h2B4, SLAM Family Member 4, SLAMF4, Signaling Lymphocytic Activation Molecule 4, 2B4, h2B4) 100ug 146828
The signaling lymphocyte-activation molecule family member 4 (SLAMF4), also known as 2B4, is an important regulator of Natural Killer (NK) cell activation.
It is expressed on NK cells as well as on subsets of T cells and interacts with SLAMF2, causing the activation of both SLAMF4- and SLAMF2-expressing cells.
Patients with systemic lupus erythmatosus have lower than normal levels of SLAMF4 expressed on their NK cells and monocytes, suggesting that SLAMF4 may play a role in this autoimmune disease.
Applications:Suitable for use in Immunofluorescence, ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1-2ug/mlOptimal dilutions to be determined by the researcher.
Positive Control:Daudi Cell Lysate
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity:Recognizes human SLAMF4. Species Crossreactivity: mouse and rat.
Isotype:IgG
Calc Applications Abbrev:E IF WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to 16aa from near the C-terminus of human SLAMF4.