Multidrug transporters, such as MFSD1, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs.
The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that include uniporters, symporters, and antiporters.
Members of this family are found in all living organisms and are highly represented in bacteria.
MFS members are capable of transporting various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific.
MFS have provided important insight into the mechanism underlying multidrug transport.
MFSD1 is still poorly understood.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1-2ug/mlImmunohistochemistry (Formalin fixed paraffin embedded): 10ug/mlOptimal dilutions to be determined by the researcher.
Positive Control:Human Lung Tissue Lysate
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity:Recognizes human MFSD1. Species Crossreactivity: mouse and rat.
Isotype:IgG
Calc Applications Abbrev:E IHC WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to 18aa from near the center of human MFSD1.