84-2113-11　BCAS1 (Breast Carcinoma-amplified Sequence 1, Amplified and Overexpressed in Breast Cancer, Novel Amplified in Breast Cancer 1, AIBC1, NABC1) 100ug　146605

特徴

• BCAS1 was identified through positional cloning and was found to be overexpressed in most but not all breast cancer cells lines.
• Little is known about this protein; BCAS1 is cytoplasmically localized and is thought to form homodimers through coiled-coil structures.
• High levels of BCAS1 mRNA are seen in brain and prostate tissues, with lower amounts observed in colon, intestine and testis.
• Cells engineered to overexpress BCAS1 did not lose anchorage-dependent growth or increase their rate of growth, suggesting that BCAS1 is not a prototypical oncogene.
• The BCAS1 gene was also found to be amplified in other carcinomas such as pancreatic carcinoma, suggesting that BCAS1 may play in important role in the control of cell proliferation.
• Applications:Suitable for use in ELISA, Western Blot, Immunofluorescence and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1ug/mlImmunohistochemistry (Formalin fixed paraffin embedded): 5ug/mlOptimal dilutions to be determined by the researcher.
• Positive Control:Human Lung Tissue Lysate
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for at least 12 months.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.