Mammalian odorant receptors require accessory proteins such as RTP1 and RTP2 for functional cell surface expression.
Receptor expression-enhancing protein (REEP) family members are transmembrane proteins which interact with odorant receptor proteins and may enhance the odorant receptor responses to odorants.
Recently studies have shown other chemosensory receptors such as bitter taste receptors are also influenced by RTP and REEP family members.
REEP3 has also been suggested as a novel candidate gene for autism and as a loci influencing the plasma levels of the liver enzyme alkaline phosphatase.
Applications:Suitable for use in ELISA, Western Blot, Immunofluorescence and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1ug/mlImmunohistochemistry (Formalin fixed paraffin embedded): 5ug/mlOptimal dilutions to be determined by the researcher.
Positive Control:Rat Lung Tissue Lysate
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity:Recognizes human REEP3. Species Crossreactivity: mouse and rat.
Isotype:IgG
Calc Applications Abbrev:E IF IHC WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:Synthetic peptide corresponding to 17aa from near the C-terminus of human REEP3.