84-2111-18　Tubulin, alpha (Alpha Tubulin, Tubulin alpha Ubiquitous, H2-Alpha, K-alpha-1, TUBA3, Tubulin alpha 1 Chain, TUBA1, TUBA1A, Tubulin K alpha 1, FLJ25113) 100ug　146411

特徴

• Alpha-tubulin belongs to the tubulin superfamily, which is composed of six distinct families.
• Along with beta-tubulins, alpha-tubulins are the major components of microtubules.
• These microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape.
• Alpha- and beta-tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22-nm diameter.
• Tyrosine ligase adds a C-terminal tyrosine to monomeric alpha-tubulin.
• Assembled microtubules can again be detyrosinated by a cytoskeleton-associated carboxypeptidase.
• Another post-translational modification of detyrosinated alpha-tubulin is C-terminal polyglutamylation, which is characteristic of microtubules in neuronal cells and the mitotic spindle.
• Like GAPDH and beta-Actin, this antibody makes an excellent loading control in immunoblots.
• Applications:Suitable for use in ELISA and Western Blot.
• Other applications not tested.
• Recommended Dilutions:Western Blot: 0.5-1ug/mlOptimal dilutions to be determined by the researcher.
• Recommended Secondary Antibodies:I1906-10: IgY, Chicken (HRP) Rb x Ch I1906-12: IgY, Chicken (FITC) Rb x Ch I1906-14: IgY, Chicken (AP) Rb x Ch
• Positive Control:Rat Brain Tissue Lysate
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.