84-2109-57 LGI2, ID (Leucine-rich Repeat LGI Family Member 2, LGI1-like Protein 2, Leucine-rich Glioma-inactivated Protein 2, KIAA1916, FLJ10675, MGC126808, MGC126810) 100ug 146249
84-2109-57 LGI2, ID (Leucine-rich Repeat LGI Family Member 2, LGI1-like Protein 2, Leucine-rich Glioma-inactivated Protein 2, KIAA1916, FLJ10675, MGC126808, MGC126810) 100ug 146249
The leucine-rich, glioma inactivated gene 2 (LGI2) is a member of the LGI family in which LGI1 is the exemplar.
The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors.
LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms.
Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI2 have not been found to be associated with ADTLE.
Applications:Suitable for use in ELISA, Western Blot, Immunofluorescence and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1-2ug/mlImmunohistochemistry (FFPE): 2.5ug/mlImmunofluorescence: 5ug/mlOptimal dilutions to be determined by the researcher.
Positive Control:Mouse Liver Tissue Lysate
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity:Recognizes human LGI2. Three isoforms of LGI2 are known to exist; this LGI2 antibody will recognize only the longest. Will not recognize other LGI proteins. Species Crossreactivity: mouse
Isotype:IgG
Calc Applications Abbrev:E IF IHC WB
Calc Crossreactivity:Hu Mo
Immunogen:Synthetic peptide corresponding to 10aa within 290-340 from the center of human LGI2.