Rift Valley Fever (RFV) virus is an arthropod-borne virus endemic to Africa that infects humans and animals that is transmitted predominantly by mosquitoes.
During human infections, symptoms can range from benign fever to severe encephalitis and fatal hepatitis with hemorrhagic fever.
The Bunyaviridae family of viruses to which the RVF virus belongs are spherical enveloped viruses with a tripartite RNA genome of negative or ambisense polarity.
The three segments are referred to as the L, M, and S segments.
The L and M segments are negative polarity and code fore the L-dependent RNA polymerase and glycoprotein precursor respectively.
The S segment is of ambisense polarity and encodes the nucleoprotein and non-structural proteins.
This RVF virus antibody was derived from a peptide sequence near the carboxy terminus of the polyprotein precursor translated from the M segment.
It will therefore detect both the precursor and the Glycoprotein G2.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:ELISA: 1ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity:Recognizes RVF virus.
Isotype:IgG
Calc Applications Abbrev:E
Immunogen:Synthetic peptide corresponding to 19aa from near the C-terminus of RVF virus.