Sarcoma (Scr) is a proto-oncogenic tyrosine kinase originally discovered by J.
Michael Bishop and Harold E.
Varmus.
belongs to a family of non-receptor tyrosine kinases called Src family kinases.
The human SRC protooncogene was assigned to chromosome 20.
Its gene is mapped to 20q12-q13.
The discovery of Src family proteins has been instrumental to the modern understanding of cancer as a disease where normally healthy cellular signalling has gone awry.
This proto-oncogene may play a role in the regulation of embryonic development and cell growth.
UniProt Number:P12931
Gene ID:SRC
Applications:Suitable for use in Western Blot.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a lyophilized powder. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity:Recognizes human, mouse and rat SRC. No crossreactivity with other proteins.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:A synthetic peptide corresponding to a sequence at the C-terminal of human SRC, identical to the related rat and mouse sequence.