Neutral amino acid transporter A, also called SLC1A4 or ASCT1, is a protein that in humans is encodes by the SLC1A4 gene.
The SLC1A4 gene is mapped to chromosome 2p14 based on an alignment of the SLC1A4 sequence with the genomic sequence (GRCh37).
ASCT1 does not transport glutamate or aspartate but alanine, serine, cysteine, and threonine instead.
It is found that the ASCT1 transporter functions primarily as an amino acid exchanger.
Transport is associated with a chloride channel activity that is thermodynamically uncoupled from animo acid transport.
This gene also exhibits sodium dependence.
UniProt Number:P43007
Gene ID:SLC1A4
Applications:Suitable for use in Western Blot and Immunohistochemistry (Paraffin).
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity：Recognizes human, mouse and rat SLC1A4. No crossreactivity with other proteins.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：A synthetic peptide corresponding to a sequence at the C-terminus of human SLC1A4, different from the related rat and mouse sequences by one amino acid.
