RGS3 (Regulator of G Protein Signaling 3), is a protein that in humans is encoded by the RGS3 gene.
Chatterjee et al.
(1997) studied RGS3, the largest member of the RGS family then identified.
Mouse Pdz-Rgs3 can mediate signaling from the ephrin-B cytoplasmic tail.
By radiation hybrid mapping, Chatterjee et al.
(1997) assigned the RGS3 gene to chromosome 9q31-q33.
Lu et al.
(2001) showed that Sdf1, a chemokine with a G protein-coupled receptor, and Bdnf are chemoattractants for cerebellar granule cells, and that Sdf1 chemoattraction is selectively inhibited by soluble ephrin-B receptor.
This inhibition could be blocked by a truncated Pdz-Rgs3 protein lacking the RGS domain.
UniProt Number:Q9DC04
Gene ID:Rgs3
Applications:Suitable for use in Western Blot and Immunohistochemistry (Paraffin).
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity：Recognizes human,mouse and rat RGS3. No crossreactivity with other proteins.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：A synthetic peptide corresponding to a sequence at the C-terminal of mouse RGS3, identical to the related rat sequence, and different from the related human sequence by two amino acids.
