PTGER1, Prostaglandin E Receptor 1, comprises 402 amino acids with a predicted molecular mass of 41,858 and has the 7 predicted transmembrane-spanning domains common to all G protein-coupled receptors.
The PTGER1 gene is mapped to chromosome 19p13.1.
The protein encoded by this gene is a member of the G protein-coupled receptor family.
This protein is one of four receptors identified for prostaglandin E2 (PGE2).
Through a phosphatidylinositol-calcium second messenger system, Gq proteins mediate this receptor's activity.
Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure.
Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin.
UniProt Number:P34995
Gene ID:PTGER1
Applications:Suitable for use in Western Blot.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity：Recognizes human PTGER1. No crossreactivity with other proteins.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：A synthetic peptide corresponding to a sequence at the C-terminal of human PTGER1
