POSTN (Periostin), also known as PN or OSF2, is a protein that in humans is encoded by the POSTN gene.
The International Radiation Hybrid Mapping Consortium mapped the POSTN gene to chromosome 13.
Gillan et al.
(2002) found that purified recombinant PN supported adhesion of ovarian epithelial cells.
Shao et al.
(2004) found that periostin was overexpressed by the majority of human primary breast cancers examined.
Transfected tumor cell lines overexpressing periostin showed accelerated growth and angiogenesis as xenografts in immunocompromised animals.
Kuhn et al.
(2007) showed that extracellular periostin induced reentry of differentiated mammalian cardiomyocytes into the cell cycle.
UniProt Number:Q62009
Gene ID:POSTN
Applications:Suitable for use in Western Blot.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity：Recognizes mouse and rat POSTN. No crossreactivity with other proteins.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Mo Rt
Immunogen：A synthetic peptide corresponding to a sequence at the N-terminal of mouse POSTN, identical to the related rat sequence, and different from the related human sequence by three amino acids.
