Ang K1-3 is a single, non-glycosylated polypeptide chain containing 259 amino acids.
It represents a proteolytic fragment of plasminogen containing the first three kringle structures.
Ang K1-3 reduces endothelial cell proliferation and acts as a potent inhibitor of angiogenesis and tumor growth.
It displays increased inhibitory activity(ED50 = 70nM) relative to kringles 1-4(ED50 = 135nM).
UniProt Number:P00747
Gene ID:PLG
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry (Paraffin).
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a lyophilized powder. Each vial contains 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity:Recognizes human Angiostatin K1-3. No crossreactivity with other proteins.
Isotype:IgG
Calc Applications Abbrev:E IHC WB
Calc Crossreactivity:Hu
Immunogen:E. coli-derived human Angiostatin K1-3 recombinant protein (Position: C103-C352).