P2X purinoceptor 7, also called P2X7, is a protein that in humans is encoded by the P2RX7 gene.
The product of this gene belongs to the family of purnoceptors for ATP.
P2RX7 was mapped to chromosome 12q24 by fluorescence in situ hybridization.
It is a receptor for ATP that acts as a ligand-gated ion channel.
This gene is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules.
It could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.
UniProt Number:Q64663
Gene ID:P2RX7
Applications:Suitable for use in Western Blot.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity：Recognizes human,mouse and rat P2RX7. No crossreactivity with other proteins.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：A synthetic peptide corresponding to a sequence at the N-terminal of rat P2RX7, different from the related mouse sequence by one amino acid, and from the related human sequence by two amino acids.
