CEREVISIAE, HOMOLOG OF, 5)，also known as CDC46, is a protein that in humans is encoded by the MCM5 gene.
MCM5 is structurally very similar to the CDC46 protein from S.
cerevisiae, a protein involved in the initiation of DNA replication.
And MCM5 is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family.
The MCM5 gene is mapped on 22q12.3.
The MCM5 gene contains 16 exons.
The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.
UniProt Number:P33992
Gene ID:MCM5
Applications:Suitable for use in Western Blot and Immunohistochemistry (Paraffin).
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity：Recognizes human, mouse and rat MCM5. No crossreactivity with other proteins.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：A synthetic peptide corresponding to a sequence at the C-terminal of human MCM5, identical to the related rat and mouse sequences.
