Lipocalin-1(LCN1),also known as PREALBUMIN, TEAR or VEGP, is a protein that in humans is encoded by the LCN1 gene.
Lipocalin-1 is a member of the lipocalin family of small secretory proteins, which is mapped on 9q34.3.
Lipocalin-1 is the primary lipid binding protein in tears and is overproduced in response to multiple stimuli including infection and stress.
It may be a marker for chromosome aneuploidy as well as an autoantigen in Sjogren's syndrome.
LCN1 inhibits the cysteine-protease papain in vitro, similar to cystatins.
And LCN1 plays a role in the nonimmunologic defense and in the control of inflammatory processes in oral and ocular tissues.
The investigations presented the first clear evidence that LCN1 is induced in infection or inflammation and supported the idea that this lipocalin functions as a physiologic protection factor of epithelia in vivo.
UniProt Number:P31025
Gene ID:LCN1
Applications:Suitable for use in Western Blot and Immunohistochemistry (Paraffin).
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity：Recognizes human Lipocalin-1. No crossreactivity with other proteins.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu
Immunogen：A synthetic peptide corresponding to a sequence in the middle region of human Lipocalin-1.
