84-2096-94　ITGA1 (CD49a, VLA1, VLA-1, CD49a, very late activation protein 1, Laminin and collagen receptor, CD49 antigen-like family member A) 100ug　144783

特徴

• Integrin alpha 1 (ITGA1) chain associates with the beta 1 (ITGB1) chain to form a heterodimer that functions as a dual laminin/collagen receptor in neural cells and hematopoietic cells.
• ITGA1 has a 206-amino acid I domain in its N-terminal half, followed by 3 divalent cation-binding sites and a C-terminal transmembrane domain with a short cytoplasmic tail.
• It also has 28 potential N-glycosylation sites.
• Human ITGA1 was expressed in a mouse fibroblast cell line as a 180-kD protein.
• ITGA1 is involved in the early remodeling of osteoarthritic cartilage and plays an essential role in the regulation of mesenchymal stem cell proliferation and cartilage production.
• It also plays an essential role in the regulation of MSC proliferation and cartilage production.
• UniProt Number:P56199
• Gene ID:ITGA1
• Applications:Suitable for use in Western Blot and Immunohistochemistry (Paraffin).
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Handling:Store at -20˚C for one year.
• After reconstitution, store at 4˚C for one month.
• Can also be aliquoted and stored frozen at -20˚C for long term
• Avoid repeated freezing and thawing.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.