Interleukin-1 receptor-associated kinase 3, also called IRAK3 or IRAKM is an enzyme that in humans is encoded by the IRAK3 gene.
The IRAKM gene consists of 12 exons spanning a region of approximately 60 kb in chromosome 12q14.3.
This gene encodes a member of the interleukin-1 receptor-associated kinase protein family.
Members of this family are essential components of the Toll/IL-R immune signal transduction pathways.
This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling.
Mutations in this gene are associated with a susceptibility to asthma.
UniProt Number:Q9Y616
Gene ID:IRAK3
Applications:Suitable for use in Western Blot.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity：Recognizes human IRAK3. No crossreactivity with other proteins.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：A synthetic peptide corresponding to a sequence at the C-terminus of human IRAK3.
