IL2RB(INTERLEUKIN 2 RECEPTOR, BETA)，also called CD122, is a protein that in humans is encoded by the IL2RB gene.The gene represents the beta subunit and is a type I membrane protein.
IL2RB is mapped to 22q12.3.
The IL2RB gene contains 10 exons spanning about 24.3 kb and that the gene product is encoded by exons 2-10.
The IL2 receptor is present in 3 forms with respect to binding ability to IL2 : high, intermediate, and low affinity forms.
Analysis of mutants of the beta chain of the IL2 receptor reveals that the granulocyte and monocyte differentiation signals are triggered by different cytoplasmic domains, showing that the signaling pathways responsible for these unique developmental outcomes are separable.
UniProt Number:P14784
Gene ID:IL2RB
Applications:Suitable for use in Western Blot.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity：Recognizes human IL2RB/CD122. No crossreactivity with other proteins.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：A synthetic peptide corresponding to a sequence in the middle region of human IL2RB.
