Interleukin-6 (IL-6) is a protein that in humans is encoded by the IL6 gene.
IL-6 is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine.
It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation.
IL-6 is one of the most important mediators of fever and of the acute phase response.
IL-6 is also essential for hybridoma growth and is found in many supplemental cloning media such as briclone.
Bowcock et al.
(1988) assigned the IL6 gene to chromosome 7p21.
By in situ hybridization and Southern blot analysis of mouse-human hybrid cell lines, Sutherland et al.
(1988) mapped the IL6 gene to chromosome 7p15.
UniProt Number:P05231
Gene ID:IL6
Applications:Suitable for use in Western Blot.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity：Recognizes human IL-6. No crossreactivity with other proteins.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：A synthetic peptide corresponding to a sequence at the C-terminal of human IL-6.
