IKBKG , (Inhibitor of kappa light polypeptide gene enhancer in B cells,kinase of ,gamma) is also know as NEMO .
The IKK complex is composed of IKK-alpha, IKK-beta, and 2 other polypeptides of 50 and 52 kD which are differentially processed forms of a third subunit, IKK-gamma.
The 419-amino acid IKK-gamma protein is composed of several potential coiled-coil motifs and a leucine zipper motif.
NEMO interacted with IKK2 (IKK-beta), but not with IKK1 (IKK-alpha).
IKK-gamma forms dimers and trimers and interacts preferentially with IKK-beta.
UniProt Number:O88522
Gene ID:IKBKG
Applications:Suitable for use in Western Blot.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:mouse
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a lyophilized powder. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity:Recognizes mouse IKBKG. No crossreactivity with other proteins.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Mo
Immunogen:A synthetic peptide corresponding to a sequence at the N-terminal of mouse IKBKG, different from the relative rat sequence by three amino acids,