Interferon-gamma (IFN-gamma) is an inflammatory cytokine that has been implicated in the development of fibrosis in inflamed tissues.
The production of IFN-gamma, which is under genetic control, can influence the development of fibrosis in lung allografts.
IFN-gamma is also produced by natural killer (NK) cells and most prominently by CD8 cytotoxic T cells, and is vital for the control of microbial pathogens.
Interferon gamma is believed to be crucial for host defence against many infections.
Genetically determined variability in IFN-gamma and expression might be important for the development of tuberculosis.
IFN-gamma activates human macrophage oxidative metabolism and antimicrobial activity.
In addition to having antiviral activity, IFN-gamma has important immunoregulatory functions.
IFN-gamma plays an important role in the control of neointima proliferation.
UniProt Number:P01579
Gene ID:IFNG
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry (Paraffin), Neutralization and Immunoprecipitation.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder. Each vial contains 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity：Recognizes human IFN gamma. No crossreactivity with other proteins.
Isotype：IgG
Calc Applications Abbrev：E IHC IP N WB
Calc Crossreactivity：Hu
Immunogen：E. coli-derived human IFNgamma recombinant protein (Position: Q24-Q166).
