LAT2 (Linker for Activation of T Cells Family, Member 2), also known as LAB or NTAL , is a protein that in humans is encoded by the LAT2 gene.
By genomic sequence analysis, Doyle et al.
(2000) mapped the WBSCR5 gene to chromosome 7q11.23.
They noted that the flanking genes are highly conserved between mouse and human.
By immunoprecipitation and immunoblot analysis, Brdicka et al.
(2002) found that NTAL associated with GRB2, SOS1, and GAB1 after B-cell receptor activation.
Janssen et al.
(2003) determined that phosphorylation of LAB is likely mediated by SYK upon B-cell receptor stimulation.
Binding analysis indicated associations with GRB2, and, indirectly, with PLCG1 and PLCG2.
UniProt Number:Q9GZY6
Gene ID:LAT2
Applications:Suitable for use in Western Blot.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity：Recognizes human h.LAT2. No crossreactivity with other proteins.
Isotype：IgG
Calc Applications Abbrev：IP WB
Calc Crossreactivity：Hu
Immunogen：A synthetic peptide corresponding to a sequence at the N-terminal of human LAT2.
