GATA2(GATA binding protein 2) is a human gene which makes a protein called GATA binding protein 2 - a transcription factor.
The GATA family of transcription factors, which contain zinc fingers in their DNA binding domain, have emerged as candidate regulators of gene expression in hematopoietic cells.
Ciciotte et al.
(1997)mapped the mouse Gata2 gene to chromosome 6 by study of DNA from an interspecific backcross panel.
They pointed out that the human gene had been mapped to chromosome 3 by Dorfman et al.
(1992) using DNA from a panel of 12 rodent/human hybrids containing various human chromosomes and applying Southern blot analysis.
By exon trapping using a PAC contig spanning a breakpoint region associated with myeloid leukemia, Wieser et al.
(2000) mapped the GATA2 gene to chromosome 3q21.
GATA2 is transcribed from telomere to centromere.
GATA2 is expressed in hematopoietic progenitors, including early erythroid cells, mast cells, and megakaryocytes, and also in nonhematopoietic embryonic stem cells.
UniProt Number:P23769
Gene ID:GATA2
Applications:Suitable for use in Western Blot.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity：Recognizes human, mouse and rat GATA2. No crossreactivity with other proteins.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：A synthetic peptide corresponding to a sequence at the N-terminal of human GATA2, identical to the related rat and mouse sequences.
