Transcription factor E2F3, also known as KIAA0075, is a protein that in humans is encoded by the E2F3 gene.
The protein encoded by this gene is a member of the E2F family of transcription factors.
By fluorescence in situ hybridization, E2F3 gene is mapped to 6q22.3.
The induction of specific E2F activities is an essential component in the MYC pathways that control cell proliferation and cell fate decisions.
This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins.
The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle.
UniProt Number:O00716
Gene ID:E2F3
Applications:Suitable for use in Western Blot.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity：Recognizes human and mouse E2F3. No crossreactivity with other proteins.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo
Immunogen：A synthetic peptide corresponding to a sequence at the C-terminal of human E2F3, identical to the related mouse sequence.
