CXCR2 is a receptor for Interleukin 8, which is a powerful neutrophil chemotactic factor.
It is a member of the GPCR family (subfamily, chemokine).
Binding of IL8 to the receptor causes activation of neutrophils.
This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system.
This receptor binds to IL8 with a high affinity and to GRO/MGSA and NAP2 also with a high affinity.
It has been reported to be expressed in a wide variety of tissues.
ESTs have been isolated from human placenta and thymus libraries.
UniProt Number:P25025
Gene ID:CXCR2
Applications:Suitable for use in Western Blot.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity：Recognizes human CXCR2. No crossreactivity with other proteins.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：A synthetic peptide corresponding to a sequence in the middle region of human CXCR2, different from the related mouse sequence by six amino acids
