Cyclin-dependent kinase 7, also known as cell division protein kinase 7, is an enzyme that in humans is encoded by the CDK7 gene.
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family.
The gene was assigned to human chromosome 5q13.2.
Serine/threonine kinase involved in cell cycle control and in RNA polymerase II-mediated RNA transcription.
CDK7 is the catalytic subunit of the CDK-activating kinase (CAK) complex.
It is required for DNA-bound peptides-mediated transcription and cellular growth inhibition.
UniProt Number:Q03147
Gene ID:CDK7
Applications:Suitable for use in Western Blot.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a lyophilized powder. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity:Recognizes human, mouse and rat CDK7. No crossreactivity with other proteins.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:A synthetic peptide corresponding to a sequence at the C-terminal of mouse CDK7, identical to the related rat sequence, and different from the related human sequence by two amino acids.