Cell division protein kinase 6, also called Plstire, is an enzyme that in humans is encoded by the CDK6 gene.
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family.
Radiation hybrid analysis and inclusion within a mapped clone place the CDK6 gene at 7q21.
Serine/threonine-protein kinase involved in the control of the cell cycle and differentiation and promotes G1/S transition.
This gene also involved in initiation and maintenance of cell cycle exit during cell differentiation.
It prevents cell proliferation and regulates negatively cell differentiation, but is required for the proliferation of specific cell types.
CDK6 also plays a role in promoting the proliferation of beta-cells in pancreatic islets of Langerhans.
UniProt Number:Q64261
Gene ID:CDK6
Applications:Suitable for use in Western Blot.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity：Recognizes human, mouse and rat CDK6. No crossreactivity with other proteins.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：A synthetic peptide corresponding to a sequence at the C-terminal of mouse CDK6, identical to the related rat sequence, and different from the related human sequence by four amino acids.
